胡志宏

研究方向：生物信息学、分子生物学、合成生物学

电子邮箱：huzhihong426@163.com

简要介绍：以工业微生物为研究对象，通过生物信息学分析，分子生物学改造，为其作为底盘细胞合成高附加值代谢产物奠定基础；目前主持或完成国家级项目2项；省部级以上5项，企业横向项目1项。

代表成果：

1.Tian Xueqin, Qin Kunhai, Deng Yunhong, Xue Pinghong, Huang Chaozheng, Liu Shaofang, Hu Zhihong*. The expression pattern, subcellular localization of Aspergillus oryzae ergosterol synthases, and their effects on ergosterol and fatty acid metabolism，Applied and Environmental Microbiology, 2025, accepted.

2.Huang Hui, Niu Yali, Jin Qi, Qin, Kunhai, Wang Li, Shang Yitong, Zeng Bin*, Hu Zhihong*. Identification of Six Thiolases and their Effects on Fatty Acid and Ergosterol Biosynthesis in Aspergillus oryzae. Applied and Environmental Microbiology, 2022, 88(6): aem0237221.

3.Tian Xueqin, Qin Kunhai, Deng Yunhong, Xue Pinghong, Huang Chaozheng, Liu Shaofang, Hu Zhihong*. Construction of a New Agrobacterium tumefaciens-Mediated Transformation System based on a Dual Auxotrophic Approach in Cordyceps militaris. Journal of Microbiol Biotechnology, 5 (2024), 1-10.

4.Sun Yunlong, Niu Yali, He Bin, Ma Long, Li Ganghua, Tran Van-Tuan, Zeng Bin* and Hu Zhihong*, A Dual Selection Marker Transformation System Using Agrobacterium Tumefaciens for the Industrial Aspergillus Oryzae 3.042. Journal of Microbiol Biotechnology, 29 (2019), 230-234.

5.Sun Yunlong, Niu Yali, Huang Hui, He Bin, Ma Long, Li Ganghua, Tran Van-Tuan, Zeng Bin* and Hu Zhihong*, Mevalonate diphosphate decarboxylase MVD/Erg19 is required for ergosterol biosynthesis, growth, sporulation and stress tolerance in Aspergillus oryzae. Frontiers in Microbiology, 2019, doi: 10.3389/fmicb.2019.01074.